Classify the departments of Colombia and their capitals, according to the behavior of the incidence of Sars-Cov2, between March 6, 2020 and February 4, 2021. The information on daily cases was obtained from the website of the National Institute of Health (INS), the population estimate for each geographic unit was obtained from the population estimated by the National Administrative Department of Statistics (DANE) for 2020. The clusters obtained for both capitals and departments were obtained by non-hierarchical classification methods. Four groups were obtained for both, capitals and departments: the coast zone, the central zone, the eastern zone and the Amazon. In most cases the classification of the capitals coincided with that of the department. The classification obtained by the k-medoid method, using the Euclidean distance, proposed groups that coincide with different epidemiological behaviors between groups and similar ones within groups, therefore it becomes a useful statistical tool for public health.