Laser inscribed graphene (LIG) is a versatile material that is commonly used to prepare electrochemical sensors (Moreira et al 2023). This protocol describes the fabrication of a 3-electrode plug-and-play chip system based on LIG. The design is compatible with a female USB-A connector which can be modified for connection to any potentiostat using the protocol here. The complete process requires approximately 60 min to complete, including fabrication of USB-A connector (Fig 1).
