To explore sustainable alternatives to meet the growing energy demand worldwide, it is necessary to analyze strategies promoting the efficient use of energy, the mitigation of environmental impact, the diversification of power resources, and the orientation toward energy transition. Due to their location, Latin America and the Caribbean have a significant renewable energy potential. For instance, Colombia has an installed thermoelectric capacity accounting for over 40% of its total power generation resources. Nevertheless, its legislation promotes the fair transition toward alternative sources while leveraging the installed infrastructure. Additionally, worldwide projections show that hydrogen-based power generation will foster the hybridization of power generation systems. This research addresses the evaluation of four increasingly complex systems, starting with a Combined Cycle Gas Turbine (CCGT), successfully adding subsystems up to a hybrid system comprising a CCGT, a photovoltaic field, a methane reformer with carbon capture, a Proton Exchange Membrane (PEM) electrolyzer, and a hydrogen compression-storage stage. The appraisal is performed with the Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS), using technical, economic, sociopolitical, and environmental indicators. We used the Colombian energy market as a case study. The evaluation found that the scenario incorporating all the subsystems achieves the best trade-off across all considered criteria. In nominal conditions, this scenario achieves an overall efficiency of 63.67%, a levelized cost of energy of 0.032 USD/kWh, a carbon footprint of 0.047 kgCO2/kWh, and a conventional-to-total power ratio of 70.77%. Integrating electrolysis, reforming with carbon capture for hydrogen generation, and using surplus gas and power reduce CO2 emissions while increasing profits. Additionally, the combination of hydrogen storage and solar energy enhances overall power generation capabilities. The proposed assessment methodology can be extended to evaluate the viability of similar hybrid systems in other regions and energy markets.