Mohs micrographic surgery is a distinguished method for excising skin cancers, especially basal cell and squamous cell carcinomas, with a high precision rate that preserves healthy tissue. This narrative review explores the indications, technique, and both preoperative and postoperative management of Mohs surgery, highlighting its advantages such as high cure rates and minimal scarring. The review also discusses potential complications and limitations, underscoring the importance of patient selection and surgical expertise. Mohs surgery remains a cornerstone in dermatological oncology for its effectiveness in treating complex skin cancers.