Hereditary hemochromatosis is a condition resulting in tissue damage by pathological iron deposition due to genetic alterations. The clinical manifestations are diverse, and depend on the involvement of the affected organ. Complications such as cirrhosis, heart failure, diabetes, and arthritis are described. Iron deposition in brain tissues with neurological damage and presence of symptoms is not a usual finding. Some case series describe movement disorders as the clinical manifestation. The authors report a patient with movement disorder due to hepato-cerebral hemochromatosis, who showed clinical improvement after diagnosis and treatment. Hereditary hemochromatosis should be considered in the differential diagnosis of movement disorders in patients with signs of iron overload.