Introduction: Non-invasive neuromodulation is extensively researched and applied as a therapeutic strategy for neuropathic pain due to its analgesic properties. Despite numerous meta-analyses and guidelines addressing this area, establishing optimal care practices for neuropathic pain individuals remains pivotal. Objective: To consolidate existing knowledge and evidence regarding the use of non-invasive neuromodulation for neuropathic pain management, we conducted this umbrella review (registration number CRD42021239577). Material and methods: Employing the PICO strategy, a systematic search was conducted on the PubMed/MEDLINE electronic database from June 2021 to February 2024. Only meta-analyses of non-invasive brain stimulation (NIBS) and neuropathic pain from clinical trials were included. Study selection, data extraction, and quality assessment through AMSTAR and GRADE were performed in pairs. Results: A total of 111 studies were screened, with 20 meta-analyses and two network meta-analyses meeting the eligibility criteria for inclusion in this umbrella review. The most commonly utilized NIBS modalities were repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS), predominantly targeting the primary motor cortex (M1) and the left dorsolateral prefrontal cortex (DLPFC). The included population covered a broad spectrum of central and peripheral neuropathic pain conditions. According to the GRADE system, the quality of evidence in most studies was rated as low or very low. Conclusion: Non-invasive neuromodulation techniques have demonstrated efficacy in pain management among individuals with central and peripheral neuropathic pain. Significant gaps in the literature have been identified, presenting opportunities for enhancing clinical practice and should be addressed in future research.