Introduction:Colombia is among the leading countries in cardiology and cardiovascular medicine in Latin America.The current demographic transition has generated greater demand for cardiovascular surgery procedures; however, with the COVID-19 pandemic situation, this has changed.Objective: to describe the demographic characteristics of patients undergoing heart valve replacements in Colombia.Materials and method: a descriptive cross-sectional study of data from the Sistema Integrado de Información de la Protección Social (SISPRO) [Integrated Social Protection Data System], taking into account the Clasificación Única de Procedimientos en Salud (CUPS) [Single Classification of Healthcare Procedures] in the category "Heart valve replacements" from 2017 -2021.Results: 10,023 heart valve replacements were performed, with a 3:2 male to female ratio, and 55% corresponded to the 60-79-year-old age group.There was a 23% reduction during the mandatory quarantine due to the pandemic.There was no significant difference between the contributory and subsidized health insurance regimens.The territorial entities with the most procedures were Bogotá, Valle del Cauca, Antioquia and Cundinamarca.The institution that performed the most procedures was Fundación Cardio Infantil in Bogotá.Conclusions: demographic and epidemiological information from SISPRO on heart valve replacements from 2017 to 2021 was reported.