Julolidine (1,7-diaryl -2,6-dimethyljulolidine) is a new compound with great interest in the industrial and medicinal areas.In the last decade, studies of these materials have shown benefits from their fluorescent properties capable of becoming the central basis of energy exchange, or in being a medicinal alternative in diseases such as Alzheimer's or Diabetes [1].These properties can vary depending on the substituents attached to the julolidinic nucleus, which poses a wide use of these compounds.1,7-bis(3-methoxy-4-hydroxyphenyl)-2,6,9-trimethyljulolidine (C29H33NO4) or JL-1 and 1-(3,4-methylenedioxyphenyl)-7-(4methoxyphenyl)-2,6,9-trimethyljulolidine (C29H31NO3) or JL-2 are a derivative of a Julolidine synthesized at the Industrial University of Santander by the CODEIM Research Group [2] through the cationic Povarov reaction of 4-methylinine and Isoeugenol as precursors.These compounds were purified through column chromatography (diethyl ether-ethyl acetate) in 2:1 ratio and crystallized under atmospheric conditions obtaining needle-shaped crystals as a result.Structure resolution and refinement was carried out through direct and least squares methods using the SHELX software package with the facility of the OLEX 2.0 v1.5 interface [3].JL-1 crystallizes in an orthorhombic system with space group Pna21 and cell parameters a = 9.2446(4) Å, b = 21.2452(8)Å, c = 25.3771(9)Å, V = 4984(2) Å3 and Z= 8, with two crystallographically independent units (Figure 1a) and JL-2 in a monoclinic system with space group P21/n and parameters a = 10.3855(11)Å, b = 10.4233(11)Å, c = 22.497(3) Å, V = 2429.6(5)Å3 and Z= 4 (Figure 1b).The JL-1 packing features hydrogen bonds, X-H••••π and π••••π interactions that give stability to the crystal lattice.Together, all interactions give rise to a tetramer-like packing that extends diagonally along the bc plane.The supramolecular analysis using Hirshfeld surface analysis was carried out with the CrystalExplorer v21.5 program [4] showing the areas with higher interactions (H••••H 69.6%, C••••H 17.1%, O••••H 10.5%) in relation to their fingerprints.For JL-2 currenlty the work is enphasys in research about in the fingersprints and the hydrogen bonds and packing between the units.Figure 1.a. Tetramer packing along the bc axes JL-1(Left) b.Packing along bc axes JL-2 (Right).