Prune Belly Syndrome is a rare disease, with incidence of 1 case per 30,000 live-born children, described since the 19th century by Frohlich, characterized by a set of congenital malformations with the triad of bilateral abdominal cryptorchidism, urinary tract malformations such as (megabladder, megaureters, urachus persistence, hydronephrosis and/or renal dysplasia) and weakness or partial or total absence of abdominal wall muscles. We report a case of a 36-week-old newborn with prenatal findings of alterations in the urinary tract via ultrasound. After birth, a very suggestive physical examination of prune belly syndrome was performed.