This article develops a hermeneutic study of Heidegger’s text The Word of Nietzsche: “God is Dead”. We attempt to read Heidegger’s remarks in the context of the “period of transition” that, according to Nietzsche, is occurring in the history of western thought and culture. This essay unfolds in the following manner: beginning with Heidegger’s contention that Nietzsche’s philosophy is the “fulfilment” of Platonism, we go over the problem of nihilism in relation to the metaphysics of the will to power, which for Heidegger requires revising Cartesian subjectivity in search of a new ontology. Heidegger’s critique of modernity encompasses a narrative that goes from “Plato” to “Nietzsche”, leading to a reconsideration of the notions of art and truth. Finally, we attempt to interpret the meaning of the “madman’s lament” voicing the passing of God.