Introduction: The purpose of investigating this documentary review is focused on making a comparison between the agricultural industry of Colombia and Brazil on all topics that cover matters related to safety issues and that promote safe work environments. In this context, we want to understand the political regulations, guidelines, and practices that govern each country, that they execute and that are directly related to creating safe environments and taking care of the health of workers involved in the field of agriculture. For which we seek to know and analyze how these guidelines that take care of the safety of workers and promote health at work in these two countries are implemented. Additionally, the effectiveness will be studied as a result of the measures taken in these two countries, where it will be determined if they fulfill the desired function, which is to provide protection and security to these workers who carry out their work tasks in the agricultural sector. The aim is to be able to provide and obtain a clearer and more detailed vision of the implementation of these two countries on the safety that is carried out in the workplace and how they prevent occupational diseases, where it seeks to contribute to improving working conditions and generating environments. healthy for these workers in the sector, in the agricultural industry in Colombia and Brazil. Objective: This review seeks to identify the main parameters that are fundamental and that have been previously established in Colombia and Brazil in the field of safety of this sector and health of workers in the agricultural sector. These parameters must be established to take care of the health of these workers, and thus be able to create safer and healthier environments. Methodology: This documentary review is carried out by examining documents at an international, national and local level taking into account a period of 5 years ago. This process is constituted by carrying out a bibliographic review, where the information from different documentary sources is analyzed and interpreted. Results: it was determined that Colombia and Brazil implement standards and regulations to guarantee the safety of workers, in Colombia and Brazil there are laws to care for the worker who performs their tasks in the field or known as rural worker, and these standards were determined They shelter all workers in general. It was also established that Brazil has a higher incidence of diseases related to chemical risk, unlike Colombia, which has an incidence of musculoskeletal disorders, and both countries face challenges with the informality of the agricultural sector and the low literacy of the agricultural sector in Colombia and Brazil.