Alienation and mercantile fetishism are two determining categories of the antagonistic social formations that allow to explain the convergence of the subjects by means of abstractions. Thus the social and practical bond of men that takes the form of an immediate relation, in which the alienation of the thinking of the subject by himself stands out, vanishes as long as the material premises of history as social production are considered. It is proposed then to emphasize the relation between alienation and fetishism, and also as an organic differentiation of an articulated totality of determinations, from which the nexus of abstraction with history is understood, without losing sight of the fact that social production is the foundation of the social relation.