Lower limb amputation causes drastic changes in basic locomotion patterns. Currently, these patterns are analyzed using a wide variety of methods, with a focus on different variables that can describe their impact on gait conditions and normal posture. Evaluating these conditions is of paramount importance because restoring a normal gait constitutes a key objective in the physical rehabilitation of amputees. Moreover, such assessments could potentially suggest different modifications to prosthetic devices. The objective is to provide a database with values of biomechanical parameters such as body weight distribution, pelvic kinematics, and gait measurements in above-knee (AK) and below-knee (BK) amputees. <br> The data are reported in a .CSV file and are organized according to the attendance of 29 patients to the tests. Each column has the information as follows: participant number; age; gender; weight; size; body mass index (BMI); amputation level; amputation laterality; amputation date; suspension system; body weight distribution percentage in each limb, the sound limb (BWD_S) and the prosthetic one (BWD_P) and the subtraction between both of them (BWD_S-P); gait velocity, cadence; two-minute walking test distance (2MWT) and stride length for each limb (STRIDE_S and STRIDE_P). <br> Also, some gait-related indexes as follows: gait symmetry index, which represents the difference between the value (expressed as a percentage) of the sound limb and that of the prosthetic limb in the stance or swing phases, denoted as SI; quality index, it evaluates individuals’ ability to correctly divide their own gait cycle between the sound and prosthetic limb steps, named as QI_S and QI_P respectively; propulsion index, it is computed based on the gradient (in degrees) between the start and end of the monopodal support phase in the anteroposterior acceleration graph for each limb during gait, and it is denoted as PROP_S and PROP_P.