<strong>Introduction</strong> These are the <em>Summary Level-data</em> as presented in: "PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity". <em>Nature Communications </em>volume 9, Article number: 2904 (2018) doi: 10.1038/s41467-018-04766-9 If you use these data please cite the corresponding manuscript, which can be downloaded here: https://www.nature.com/articles/s41467-018-04766-9. When you have any questions or comments regarding this study or these files, please contact me via: Jessica van Setten, PhD | <em>Department of Cardiology, University Medical Center Utrecht, Utrecht University</em> | j.vansetten [at] umcutrecht [dot] nl <strong>Files and description</strong> The file PR_interval_July2018_summary_results.txt is gzipped and contains the PR interval GWAS meta-analysis summary results of 92,000 European samples. The imputation reference panel used for most studies was HapMap2 (please note: hg18, build36). <em>SNP</em> - variantID (rsID). <em>CHR</em> - chromosome numbers [1-22 and X]. <em>POS</em> - base pair position, hg18 / build36. <em>CODED_ALLELE</em> - coded allele, <em>i.e.</em> the effect allele, as represented (and harmonized) across cohorts. Note that this is not necessarily the minor allele. <em>NON_CODED_ALLELE</em> - the other allele, <em>i.e.</em> the non-effect allele. <em>CODED_ALLELE_FREQ</em> - coded allele frequency, <em>i.e.</em> the effect allele frequency. Note that this is not necessarily the minor allele frequency. <em>BETA_FIXED</em> - beta from the fixed-effects model. <em>SE_FIXED </em>- standard error from the fixed-effects model. <em>P_FIXED </em>- P-value from the fixed-effects model.
Tópico:
Cardiac electrophysiology and arrhythmias
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FuenteZenodo (CERN European Organization for Nuclear Research)