The Andean forests of Colombia harbor high plant biodiversity, especially orchids. Here, we propose and describe a new species of Campylocentrum from the cloud forests of the eastern Andean slopes of Caquetá, Colombia. The new species resembles C. alvesii, from which it differs by the longer lip with obtuse lateral lobes, and C. asplundii, from which it differs by inflorescences shorter than the leaves, trilobed lip, and strongly recurved spur.