Thrombocytopenia is a common hematologic disorder in pregnancy, presenting challenges in both diagnosis and management. This comprehensive review aims to provide an overview of thrombocytopenia in pregnancy, including its denition, etiology, diagnosis, and management strategies. Thrombocytopenia is dened as a platelet count <150,000/microL and can be caused by a variety of factors, including gestational thrombocytopenia, immune thrombocytopenic purpura, and preeclampsia. Accurate diagnosis is essential to guide appropriate management, which may include close monitoring of platelet counts, treatment with corticosteroids or intravenous immunoglobulin, and, in severe cases, platelet transfusions. The optimal management approach depends on the underlying cause of thrombocytopenia, as well as the patient's clinical presentation and gestational age. Collaboration among obstetricians, hematologists, and other specialists is crucial for the comprehensive care of pregnant women with thrombocytopenia. Overall, with careful monitoring and appropriate management, most women with thrombocytopenia can have successful pregnancies and deliveries. Further research is needed to improve our understanding of thrombocytopenia in pregnancy and to optimize management strategies for affected women.