Cali, Colombia has been a destination for migrants from Venezuela, either to serve as a transit point or a settlement for those seeking better opportunities. This complex situation, within the context of an intermediate city located in the Global South, has led to unprecedented institutional challenges related to the assurance of Economic, Social, and Cultural Rights (ESCR), and even more, requirements for social coexistence. This paper aims to elucidate tensions that have arisen in the social integration of the migrant population in Cali, Colombia, based on the analysis of their access to health and work rights. The primary reference for this exploration is drawn from oral accounts provided by Venezuelan migrant participants residing in the city.