The accelerated changes in society driven by the fourth industrial revolution have led to new paradigms in the economy, which in turn has generated new challenges that require professionals to develop skills that would make them better suited to respond to them. Technology-based firms are no strangers to this phenomenon; their knowledge-centred dynamics have made them a favourable scenario for the incorporation of professionals with the right combination of skills that will enable them to take on the challenges imposed by society. The contribution of this works provides a basis of information on identified and categorised skills inherent to NTBFs within the context of the 4IR, in order for recruiters, trainers and policymakers have information relevant to design strategies, programs and action plans for strengthening the skills required to respond to challenges faced by these professionals in a volatile, uncertain, complex, and ambiguous environment.