To explore sustainable alternatives to meet the growing energy demands worldwide, it is necessary to analyze strategies promoting the efficient use of energy, the mitigation of environmental impact, the diversification of power resources, and the orientation toward energy transition. Colombia has an installed thermoelectric capacity accounting for over 40% of its total power generation resources. Nevertheless, this country has a significant renewable energy potential due to its location. Additionally, projections show that hydrogen-based power generation will foster the hybridization of power generation systems.This research addresses the setting up, simulation, and evaluation of four increasingly complex systems, starting with a combined cycle gas turbine (CCGT), successfully adding subsystems until we have a hybrid system comprising a CCGT, a photovoltaic field, a methane reformer with carbon capture, a PEM electrolyzer, and a hydrogen compression-storage stage. The appraisal is performed with the Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS), using technical, economic, sociopolitical, and environmental indicators. We used the Colombian energy market as a case study.The comprehensive evaluation revealed that the scenario incorporating all the subsystems is the optimal configuration. In nominal conditions, this scenario achieves an overall efficiency of 63.67%, a levelized cost of energy (including the hydrogen vector) of 0.032 USD/kWh, a carbon footprint of 0.047 kgCO2/kWh, and a conventional-to-total power ratio of 70.77%. This configuration represents the best trade-off across all considered criteria. The integration of electrolysis, reforming with carbon capture for hydrogen generation, and the utilization of surplus gas and power reduce CO2 emissions while increasing profits from the energy vector. Additionally, the combination of hydrogen storage and solar energy via photovoltaic panels enhances overall power generation capabilities. The proposed assessment methodology can be extended to evaluate the viability of similar hybrid systems in other regions and energy markets.