The degradation process implemented by the 'Research Seedbed on Degradation of Contaminating Plastic Polymers' at Pontifical Javeriana University, using the microcosmos, aims to simulate an environment for the growth of microorganisms to biodegrade plastics. However, this system does not monitor or control the optimal conditions for the microorganism, which may lead to its inhibition. Therefore, a laboratory-scale solid-state fermentation bioreactor was developed for the degradation of oxobiodegradable plastics, utilizing Phanerochaete chrysosporium. The results in material change showed greater biodegradation compared to the microcosmos, as assessed by roughness, hydrophobicity, and reduction of functional groups. This underscores that the prototype's development makes it a viable and scalable alternative for plastic biodegradation.