The use of internal combustion engines in economic sectors such as transportation and industry has led to serious environmental problems that are reflected in global warming and climate change. Therefore, it is urgent to look for alternatives that favor the increase in efficiency and the reduction of polluting emissions in the engine. Among the alternatives, alcohols stand out due to their renewable nature, as is the case of BA blends. In this investigation, a comparison between pure gasoline and three blends of BA (butanol- acetone) identified as BA4%, BA8%, and BA12% is made. A spark ignition engine has been used for the research, which has operated under four load conditions (25%, 50%, 75%, and 100%) with a constant speed of 2400 rpm. The study involves the analysis of energy balance, emissions, performance parameters, and combustion conditions. The research results show that BA blends have the potential to reduce significantly HC, CO, and NOx emissions by 10.18%, 6.88%, and 5.32%, respectively. However, BA blends have a reduced lower calorific value and a high latent heat of vaporization, which negatively affect engine performance parameters. The research shows a reduction of BTE by 2.36% and an increase of BSFC by 4.78%. Additionally, a 5.32% to 9.05% decrease in peak pressure and heat release rate is observed. Due to this situation, it is necessary to use additives to improve the physicochemical characteristics of the BA blends.