This paper reports on a mixed methods study which explored whether English medium instruction (EMI) fosters the development of intercultural competence (IC) in students (n = 91) in eight courses taught by seven professors in two Colombian universities. Voluntary participants, through surveys, focus groups, and interviews, perceived that students developed IC, although somewhat unintentionally. This result cannot be solely associated with the EMI approach, but other classroom-related factors such as the international/intercultural nature of the course, teacher pedagogy, and/or the international/intercultural profile of the professor played a decisive role in this development. This study strengthens the research on the EMI-intercultural competence connection.