This paper analyzes the necessity and operation of conceptual macromolecule inside Edgar Morin’s school of thought due to the significant connection of his epistemological proposal and the language transformation with which the knowledge of reality is expressed in complex thought. This paper is organized as follows. First, we pointed the essential link between conceptualizer/observer subject and the macro-conceptualization. Second, we interpret the system or complex basic unity expounded in Method I based on complexity principles. Finally, it may be concluded that the linguistic resources used by this paradigm are in accordance with the new ways to understand complexity.