This research aims to determine the current conditions of geographical accessibility to and from healthcare centres in Manizales and Villamaría conurbation through the Enhanced two- step floating catchment area (E2SFCA) method, supported by geographic tools and socioeconomic assessments. The main result is that the average number of beds per 1000 inhabitants in low complexity systems is below the average defined for Colombia and Latin America, thus requiring greater attention in implementing beds to reach the required accessibility levels. These valuations allow concluding that the accessibility of healthcare institutions requires the use of significant calculation tools, such as the E2SFCA method, which has not had great applications within the Colombian territory.