Kaposi's sarcoma (KS) is a rare multifocal angioproliferative neoplasm of endothelial cells with predominantly cutaneous involvement. It was first described in 1872 by Moritz Kaposi. Four groups of KS have been classically described: classic, epidemic or AIDS-associated, iatrogenic and endemic. KS is the most frequent neoplasm associated with AIDS-associated human immunodeficiency virus (HIV) and occurs most frequently in the cephalic region (eyelids, nose and ears). This article describes the case of a 31-year-old male patient diagnosed with HIV and Kaposi's sarcoma with visceral involvement.