Diabetes is a growing clinical and public health problem. The International Diabetes Federation estimates that 537 million adults 20-79 years of age are living with diabetes worldwide and that by 2045, the number will increase to 783 million (1). This timely and important issue of Frontiers in Endocrinology addresses new population and clinical strategies for the prevention of type 2 diabetes. Investigators from around the world describe risk factors for prediabetes and type 2 diabetes, screening for risk of type 2 diabetes, and interventions to prevent type 2 diabetes. Investigators describe skipping breakfast as an independent risk factor associated with prediabetes among Japanese adolescents (https://www.frontiersin.org/articles/10.3389/fendo.2023.1051592/full) and depression and post-traumatic stress disorder following the great east Japan earthquake, tsunami, and nuclear disaster as independent risk We hope that this collection of papers will provide you with insights about new opportunities and strategies to address the pandemic of type 2 diabetes.