Summary The article presents a detailed study of the complex hydrological system that encompasses the Sierra Nevada del Cocuy, Güicán, and Chita in Colombia, and its impact on the departments of Casanare, Boyacá, and Arauca. This system is composed of multiple sub-basins, such as those of the Orozco River, Bojada River, and Nevado River, which contribute to the water supply in the region. The study focuses on the Orozco River basin and utilizes formulas for morphometric characterization of basins developed by the National University of Colombia and the Colombian Geological Service. These formulas enable the analysis of various parameters to characterize the basin. It is determined that the Orozco River basin has an elongated shape with a gentle slope, indicating a poorly drained area with slow hydrological responses. This morphometric analysis is essential for a better understanding of the overall sub-basin system and optimizing the use of this crucial resource without compromising its conservation. The study provides valuable information for the sustainable management of water resources in this significant region of Colombia.