The Equine Glandular Gastric Disease (EGGD) has few prevalence studies and no clarity on the predisposing factors and pathophysiological mechanisms. This study aimed to determine and compare the postmortem occurrence of EGGD and other gastric lesions in Colombian equids (horses, donkeys, and mules). A total of 300 equine stomachs, 100 of each group, were obtained immediately after slaughter. The postmortem examination considered the inspection of the ventral fundus, the adjoining area of the Margo plicatus, and the pyloric antrum of the glandular mucosa and the classification of the lesions. The global presence of EGGD in the equid population of the study was 68.3% (45%, 77%, and 83% for horses, donkeys, and mules, respectively), compromising the fundus and pyloric antrum. Inflammatory processes were similar between donkeys and mules, and different in horses in this mucosa. Other gastric lesions were also described. The presence of EGGD was comparatively evidenced in the three groups of equids.