A fundamental aspect of caring for neurocritical patients is interpreting and understanding their neurological signs and symptoms.This will be a helpful key to determining the brain injury or dysfunction's location, extent, and severity.The semiotics of the neurocritical patient encompasses various domains, including motor, sensory, cognitive, and autonomic functions.A comprehensive understanding of the semiotics of the neurocritical patient empowers clinicians to make timely and accurate diagnoses, predict outcomes, and implement targeted therapeutic interventions.It also enables effective communication among the interdisciplinary team members involved in the patient's care.This article review shows the importance of accurately recognizing and deciphering these signs to guide clinical decision-making.