Dry reforming of methane (DRM) is an attractive reaction as it enables the simultaneous conversion of two greenhouse gases into syngas. While Ni-based catalysts in powder form exhibit good performance in this reaction, they suffer from limited industrial applicability. In contrast, structured monolithic catalysts can overcome this drawback. In this sense, we present the synthesis of Ni-Mg-Al mixed oxide-type catalysts, both in powdered and immobilized forms, promoted with varying amounts of Ce (0-7 wt. %). We employ the coprecipitation method and slurry coating from hydrotalcite precursors for catalyst preparation. Our research also explores the role of Ce as a promoter and the impact of immobilizing the mixed oxides (MO) within cordierite monoliths on the physicochemical properties and catalytic performance of non-reduced materials in the DRM at 700 °C. Our findings reveal the favorable impact of Ce on the physicochemical properties of the catalyst, including smaller crystallite sizes, enhancing CO2 adsorption, and reducing Ni nanoparticle sizes with higher Ce content. The immobilized MO retained its crystalline structure and formed layers of varying thicknesses in the monoliths. All catalysts exhibit activity in DRM, maintaining H2/CO ratios near 1.2, with Ce improving stability and reducing coke formation, particularly at lower WHSV values. The catalytic evaluation also demonstrates that immobilizing MO in monolithic structures is highly advantageous for potential industrial scale-up, given their exceptional performance, recoverability, and reusability in subsequent catalytic tests.