<h3></h3> <b>Please confirm that an ethics committee approval has been applied for or granted:</b> Not relevant (see information at the bottom of this page) <h3>Background and Aims</h3> Glossopharyngeal neuralgia (GN) prevalence in pediatrics is unknown(1). Common causes are schwannoma(2) and Chiari malformation(3). Pharmacotherapy is the cornerstone with a poor efficacy around%(4). Invasive treatment has been described(5) ,but there is not date about the use of pulsed radiofrequency (PRF) on pediatric patients with GN, although in adults there are some(6). We present a successful case of a child with primary GN treated with PRF. <h3>Methods</h3> A 9-year-old female with a history of one year of GN unresponsive to medical treatment was referred to our pain clinic. She had a glossopharyngeal nerve block with complete pain relief for 2 weeks. Because the short-pain-relief a PRF was scheduled. After informed consent, using GA with aseptic conditions using ultrasound with a linear-high- frequency-transducer, the styloid process and the carotid artery were identified. An in-plane approach toward the posterior aspect of the styloid using hydrodissection with saline with a further Contrast injection verifying with fluoroscopy the final target. Because she was under GA no sensitive stimulus was delivered. PRF was performed with 2 cycles of 42C/4minutes/85volts. Then 3ml of bupivacaine-0.5% without epinephrine plus 2 milligrams of dexamethasone were administered (figures 1,2) <h3>Results</h3> There were not complications recorded during or after the procedure. The patient experienced a pain relief of 60% during the first week, and a continues benefit of 85% during a 6-month-follow-up. <h3>Conclusions</h3> PRF may represent an interesting therapeutic alternative and minimally invasive option in pediatric population. Further studies are needed to stablish the role of PRF in craniofacial pain in pediatrics. <h3>Attachment</h3> Glossopharyngeal neuralgia case.pdf