Objective: This paper aims to: (1) identify the factors that influence K-Economy readiness in higher education; (2) map the factors that influence K-Economy readiness based on the four pillars of K-Economy; and (3) analyze the implications of factors influencing K-Economy readiness for the role of higher education in the K-Economy era. By knowing the factors that influence K-Economy readiness, the results of this study can make a practical contribution to higher education in the world so that it can fully participate and be ready to compete in the K-Economy era. Methodology: This paper uses a systematic literature review to answer research questions, while the PRISMA technique is used to collect and screen Scopus and WoS articles from 2000 to 2022. Results: This paper finds nine factors influencing K-Economy readiness in higher education. The nine identified factors refer to the competencies needed in the K-Economy era. Discussion and conclusions: Strategic external partnerships with higher education must be done continuously in the future. Workers and employers continue to prioritize education as the nature of work has changed, and there is a need for those who work to continuously improve their skills. Higher education should emphasize exceeding student expectations by examining the demands of the target job market to fulfill those needs.