< 32 weeks of gestation (aOR 0.70; 95% CI 0.56-0.89)remained significantly lower after the implementation of universal TVU-CL.There was a trend toward lower risk of sPTB < 37 weeks (aOR 0.89; 95% CI 0.79-1.00)after implementation of universal TVU-CL, however, the risk of sPTB < 34 weeks became non-significant.Conclusions: This meta-analysis showed a significantly lower rate of sPTB after the implementation of a universal TVU-CL screening that correctly identifies pregnant individuals at high risk of sPTB who may benefit from intervention and should therefore be advocated.