Surgical Site Infection (SSI) is an infection occurring within 30 days of surgery near the surgical site. It can be categorized as supercial or deep incisional or involve organ/space infections. The incidence of SSI varies widely (5-30%), affecting 2-5% of inpatient surgical cases annually in the US. Risk factors include patient health, surgical technique, and contamination level. Objective tools like ASEPSIS and patient-centered wound questionnaires aid SSI assessment. Diagnosis involves direct wound examination, imaging, and culture analysis. Treatment includes wound exploration, debridement, and drainage of infected uid. Wound management with serial dressing changes or negative pressure wound therapy helps facilitate healing