Delirium is a complex medical condition that poses challenges for healthcare professionals. While no single intervention completely prevents delirium, non-pharmacological approaches targeting modiable risk factors show promise in reducing its incidence. These interventions include orientation protocols, cognitive stimulation, sleep facilitation, early mobilization, and the use of assistive devices. Delirium management requires a comprehensive approach, involving early recognition, multidisciplinary assessment, non-pharmacological interventions, family involvement, and judicious use of pharmacotherapy when necessary. Regular reassessment and tailoring of treatment, integration of palliative care, and ongoing education for healthcare providers are vital components. The long-term impact of delirium on older adults' health is signicant, leading to extended hospital stays, cognitive decline, increased mortality, and institutionalization. Addressing delirium with prevention, early intervention, and evidence-based practices is crucial for improving outcomes in vulnerable populations, especially those with pre-existing conditions like Alzheimer's Disease.