Orphan drugs are a medicinal product used to prevent, treat and diagnose rare diseases. These drugs have become a social problem because the pharmaceutical industries have no desire to produce these drugs due to the high cost and small demand in the market. In the United States, an orphan drug act was created that facilitates and promotes the production of these medications. These drugs have to go through a designation process where a formulary has to be filled so the FDA can approve these products. Most of the time a sponsor takes care of this due to the high cost of the drug.