Neonatal Abstinence Syndrome refers to the signs and symptoms experienced by newborn infants when they are no longer exposed to substances, drugs, or narcotics their mothers used during pregnancy. To characterize the non-pharmacological nursing care provided to newborn infants with Neonatal Abstinence Syndrome. Descriptive study using a scoping review of the literature. Five databases were searched for original articles published between 2016 and 2021 on the nursing care of newborns with NAS. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement, nine articles were selected for the qualitative synthesis. Different non-pharmacological care interventions for newborns with NAS were identified and grouped into five categories. Non-pharmacological nursing care for newborns with NAS addresses feeding methods, environmental control, alternating therapies, and soothing techniques. These care options are essential to developing appropriate nursing care plans for these subjects of care.