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Design, synthesis, in silico, and in vitro evaluation of benzylbenzimidazolone derivatives as potential drugs on α-glucosidase and glucokinase as pharmacological targets

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Abstract:

An in silico assay was designed, and generated compounds were studied to delimitate the synthesis by microwave irradiation–conventional heat combination. In vitro evaluation as antihyperglycemic and hypoglycemic agents were made, where 2s has good potential.

Tópico:

Pancreatic function and diabetes

Citaciones:

Citations: 3
3

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Información de la Fuente:

SCImago Journal & Country Rank
FuenteRSC Advances
Cuartil año de publicaciónNo disponible
Volumen13
Issue31
Páginas21153 - 21162
pISSNNo disponible
ISSNNo disponible

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Artículo de revista