A bstract Results are presented on a search for CP violation in the production and decay of top quark-antiquark pairs in the lepton+jets channel. The search is based on data from proton-proton collisions at $$ \sqrt{s} $$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msqrt> <mml:mi>s</mml:mi> </mml:msqrt> </mml:math> = 13 TeV, collected with the CMS detector, corresponding to an integrated luminosity of 138 fb − 1 . Possible CP violation effects are evaluated by measuring asymmetries in observables constructed from linearly independent four-momentum vectors of the final-state particles. The dimensionless chromoelectric dipole moment of the top quark obtained from the observed asymmetries is measured to be 0 . 04 ± 0 . 10 (stat) ± 0 . 07(syst), and the asymmetries exhibit no evidence for CP-violating effects, consistent with expectations from the standard model.