Kennedy Terminal Ulcers (KTU) are unavoidable lesions, they appear suddenly and evolve in hours, they are generally located in the sacrum or coccyx, they have a butterfly or horseshoe shape, they can be purple, red, yellow, blue and black. They generally occur at the end of life. Objective: to identify the interventions that nursing performs for the approach of the Kennedy Terminal Ulcers in patients at the end of life, according to the scientific literature between the years 2012 to 2022. Methodology: a secondary study of integrative literature review was conducted, following the steps of Whittemore and Knafl, the process of collection and analysis is presented in the diagram of the PRISMA statement. Results: There are qualitative descriptive studies and integrative reviews, an observational study and a retrospective study. The interventions implemented for the approach to KTU are varied, some aimed at the comfort and well-being of the patient at the end of life, others similar to those used for conventional PPU, guided by nursing diagnoses and the NANDA, NIC, NOC taxonomy. Conclusion: Knowing how to distinguish between a preventable PU and an unavoidable PU is of great importance for nursing interventions, since they would be more appropriate for the care of end-of-life patients with Kennedy Terminal Ulcers. On the other hand, the interest of continuing research in this thematic area is highlighted, with analytical observational or experimental studies. Key words: Kennedy Terminal Ulcer, end of life, oncologic, non-oncologic, nursing approach palliativ.