In the subregion of La Paz Province in eastern Antioquia, Colombia, hydrangea floriculture has boosted economic and social development, generating high value in the territory; however, there are still environmental gaps to be established as a sustainable activity. This study analyzed the environmental aspects of hydrangea cultivation using life cycle assessment under ISO 14040/14044 standards, defining as a functional unit 1 kg of hydrangea stems, grown on a small farm of 0.45 ha in a production cycle of 36 weeks, packed and transported for export. With gate-to-gate limits, considering activities prior to cultivation, cultivation, harvest, post-harvest, transport to the marketer and some transversal processes for the end of the cycle. The environmental impacts were evaluated using the CML methodology, Umberto LCA software and the Ecoinvent 3.8 database. It was found that the greatest contribution to these impacts is due to the application and upstream processes of chemical fertilizers and pesticides, the generation of plant residues and the use of fossil resource materials such as polymers and fuels. Two cleaner production initiatives were evaluated: composting plant residues for fertilizer and Integrated Pest Management (IPM) with biological control and natural agents to reduce the application of pesticides. The application of 100% and 50% composting of plant residues reduced the environmental load by 19.63% and 9.97%, respectively. Biological control and natural agents to replace 30% and 50% of chemical pesticides would achieve a reduction in the environmental load of 6.62% and 11.03%, respectively. The integration of both actions, with 50% composting of plant residues and 30% substitution of chemical pesticides, would reduce the total environmental load by 16.59%. Therefore, the research provides information that, when implemented, will reduce environmental impacts, generate added value by optimizing resource consumption and contribute to the sustainable development of floriculture in the province of La Paz.