In this systematic review, the aim was to describe the social determinants that influence adherence to treatment in patients diagnosed with Diabetes Mellitus 1 (DM1).A systematic bibliographic search was carried out in the databases: Mendeley, PubMed, Web of Science and Cuiden.Descriptive, observational, and intervention studies were selected that met the criteria of the PRISMA statement.Data on authors, objectives, results and conclusions of works that included variables such as: social determinants of health, adherence to treatment, patients with type 1 diabetes mellitus were collected.341 articles were found, to which 32 additional references were added.through the free search, for a total of 373 elements.After filtering using the PRISMA flowchart, 32 articles met all the criteria and of these, 18 were finally selected according to the study variables.It was possible to conclude that: The knowledge acquired about the disease through the education given by endocrinologists and nurses, family support, being a woman, high socioeconomic level and having technological control and treatment devices, are the social determinants that most influence the adherence.