The development of nations is based on the work carried out by individuals.The concern is that the benefit is represented in the economic and social development.Above all, the processes, materials, and conditions for the production of goods or services in which individuals must be considered.These can to some extent generate risks to human health and the environment, which can be aggravated if the majority lack social protection, rights at work and decent working conditions.The results of a study that sought to recognize the labor and safety conditions at work of informal merchants in the city of Bogotá are presented, an important issue, if they are considered, they are people who, in their effort to provide better well-being to their Due to the low opportunities that developing countries experience, families are forced into informality, lacking social protection, and working conditions.It is a mixed descriptive and correlational study made to informal merchants in the city of Bogotá: 58% women and 42% men, between 20 and 65 years of age.An approach was made with 96 informants through a form developed from the Colombian Technical Guide -GTC 45-.The results allowed us to know the high exposure to different factors that generate occupational diseases, as well as the low selfcare culture of those who carry out activities informally on the streets of Bogotá.