The increase of revision surgeries in hip replacement procedure in Colombian young adult population can be addressed by a new design of femoral stem that reduces stress shielding. A new femoral stem was designed using topology optimization as a design aid to reduce the mass in the femoral stem and its overall stiffness, combined with the theoretical, computational, and experimental assessment of the new design that complies with a static and fatigue safety factor greater than one. The new femoral stem design can be used as a design tool to reduce the number of revision surgeries caused by stress shielding.