We present the clinical case of a 48-year-old male patient with a history of penetrating ocular trauma in the left eye (OS). The patient presented to the clinic with a sclerocorneal wound treated in another center, aniridia, aphakia, and retinal detachment. His best-corrected visual acuity was hand motion in the injured eye. After a complete ophthalmological evaluation, C3 proliferative vitreoretinopathy was evidenced. The elected surgical technique was scleral buckling plus silicone oil retention sutures plus pars plana vitrectomy (PPV) plus 270° retinectomy plus silicone oil (SO) as tamponade. After 10 months, the patient presented a clear cornea, formed anterior chamber (AC) was present, and a red reflex with attached retina was also present.