The seismic site effect is influenced by the soil's dynamic properties.These properties are affected by the soil´s water content, which varies according to climatic conditions.This work aims to analyze the seismic site effect of a thirty-meter soil column which has different water table levels.An evaporation simulation is conducted on these columns.The mechanical properties under different suction pressures were obtained from previous research.Then, a finite-difference model was used to simulate the soil-environment interaction and the results were applied to build the water profiles of the column.Finally, a finite element model was used to simulate the seismic response at the top of the deposit.The results showed a remarkable difference in soil response according to the degree of saturation of the column.The change in saturation due to climate conditions does not have a significant effect.On the other hand, the results showed that the water table level affects the response of the deposit.The deposit with dryer conditions had a greater response acceleration in the surface than the deposit in a wetter state.This work opens many research possibilities, where the influence of water content and climate conditions in soil's mechanical and dynamical properties can be studied.These investigations would help achieve a better understanding of soil behavior and its interaction with the environment.