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Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia as a Rare Cause of Persistent Cough and Hemoptysis: A Case Report

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Abstract:

Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is an extremely rare but underdiagnosed pulmonary disorder at the benign end of the neuroendocrine cell proliferation spectrum of preinvasive lung lesions.The cause of DIPNECH is currently unknown.The diagnosis can be suggested when chest CT demonstrates characteristic findings, including multiple non-calcific bronchocentric random nodules and mosaic attenuation.DIPNECH should be considered in differential diagnoses of patients with pulmonary symptoms and chest CT findings of nodules with mosaic attenuation.It is vital to recognize it since it is thought to be a precursor of peripheral carcinoid tumors.Contrary to the literature, many peripheral carcinoid tumors developed relatively quickly and caused severe hemoptysis due to hypervascularity.The patient differs considerably from other cases in the literature regarding the clinical course, with bone involvement at the initial diagnosis and liver metastases that quickly spread and developed calcification.

Tópico:

Neuroendocrine Tumor Research Advances

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Información de la Fuente:

SCImago Journal & Country Rank
FuenteRespiratory Case Reports
Cuartil año de publicaciónNo disponible
Volumen12
Issue1
Páginas30 - 35
pISSNNo disponible
ISSN2147-2475

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