Objective:The aim of the study was to synthesize and critically assess the recommendations on neurocognitive management of patients with congenital heart disease (CHD) presented in clinical practice guidelines and scientific statements.Methods: A systematic review of practice recommendations (PROSPERO CRD42020205202).PubMed, SCOPUS, Ovid/ Cochrane, and LILACS was searched, and repositories of scientific societies and references of included documents were reviewed.Critical appraisal was performed using the Appraisal of Guidelines for Research and Evaluation (AGREE)-II (ideal scenario) for the guidelines and statements, and recommendations were assessed using the AGREE-REX (ideal and local scenarios).A matrix of recommendations and analysis of potential barriers for their implementation in Colombia is presented.Results: Eighteen related recommendations were included in the study.The average AGREE-II was 89.6.The average AGREE-REX was 90.1 in the ideal setting and 69.9 in the local setting.The included recommendations focus on surveillance, screening, evaluation, and counseling; no recommendations on neurocognitive interventions were identified.The main implementation barriers in Colombia are the healthcare system's unwillingness to pay, and the lack of a comprehensive care package for neurocognitive management in CHD.Conclusion: The identified recommendations could be adapted into a Colombian practice guideline, with modifications for the local context.