Exercise improves quality of life and life expectancy and its benefits outweigh its associated risks.However, athletes are at risk for sudden cardiac death, which occurs more frequently in them than in sedentary people, secondary to silent heart disease.Pre-participation evaluation varies by country and is a challenge for physicians in deciding whether to clear an individual for exercise or sports.Resistance training carries additional risks secondary to the cardiovascular adaptations it causes, such as cardiac remodeling, which may become pathological and increase the risk of arrhythmias, thus leading to sudden cardiac death.The main objective of this article is to propose a pre-participation evaluation in different age groups, based on current evidence in the literature for detecting and preventing cardiovascular diseases which can lead to sudden cardiac death in an athlete during sports practice.