Introduction: Headache is one of the most common complaints worldwide with a lifelong prevalence of 96% in the general population. The worldwide prevalence of secondary headaches is estimated to be 18%. Running an extensive work-up, including imaging and blood tests are not recommended in every headache patient, since the risk of false-positive results and incidental findings is high. The SNNOOP10 list was proposed to identify red flags for secondary headaches. “Pattern change or recent onset of new headache” is one of the red flags in SNNOOP10.